Brooklyn College, CUNY · Department of Biology
Bioinformatics Lab Brooklyn College — applying computer modeling to address important biological questions.
About
Shaneen Singh is a professor of biology. Although trained as an experimental biologist, she has transitioned into the field of computational biology. The long-term research goal of her lab is to apply computer modeling to address important biological questions. She teaches courses in bioinformatics and mentors students both at the undergraduate and graduate level.
Meet the Team →Lab Software
Free bioinformatics tools developed by the Singh Lab.
Consensus secondary structure prediction combining PSIPRED, JPred4, SABLE, SSPro, YASPIN, Predator, and NetSurfP-2.0 with majority voting and optional PDB lookup.
Submit a sequence or UniProt/NCBI accession and run automated homology search, Pfam domain annotation, signal peptide and TM topology prediction — with a domain architecture figure and downloadable report.
A cleaner interpretation layer on top of ProtPipe for domain architecture, topology, and functional-site context.
Open StructMap →Focused intrinsic-disorder analysis with low-complexity regions and a built-in secondary-structure overlay.
Open DisorderPred →Research
Our work spans computational structure analysis, venom biology, genome-wide domain modeling, and molecular simulation.
In silico domain architecture, protein-protein interactions, and motif analysis across diverse protein families.
Computational analysis of venom peptides and extracellular vesicle cargo from parasitoid wasps.
Characterization of protein domain families including PH domains and kinase domains across genomes.
All-atom simulations to study peptide aggregation, amyloid fibril formation, and structural dynamics.
News
Updated with support for 8 prediction servers, real-time progress tracking, PDB structure integration, and consensus majority voting.
Prof. Singh serves as guest editor of the Special Issue "Computational Approaches in Mechanisms of Pathogenesis" in the open-access journal Pathogens.
Chou et al. (including Singh S.) publish "Venomous Cargo: Diverse Toxin-Related Proteins Are Associated with Extracellular Vesicles in Parasitoid Wasp Venom." Pathogens 14(3). doi: 10.3390/pathogens14030255.
doi: 10.3390/pathogens14030255 ↗